Anxiety in Cancer Survivors

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Published

2025-12-19

DOI:

https://doi.org/10.54169/ijocp.v5i02.12

Keywords:

Anxiety, Cancer patients, survivorship care

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Issue

Vol. 5 No. 02 (2025): Indian Journal of Clinical Psychiatry

Section

REVIEW ARTICLE

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Copyright (c) 2025 Simhachalam Gurugubelli, Prasad Rao, Nitesh Mutyala, Arvind Kunadi, Uma Devi Avasarala, Shivangini Singh

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Authors

  • Simhachalam Gurugubelli Clinical Assistant, Professor of Medicine, Indiana University School of Medicine
  • Prasad Rao Director of Schizophrenia Clinic and Psychopharmacology, Dean of Academic Affairs, Asha Hospital
  • Nitesh Mutyala Clinical Assistant, Professor of Medicine, Indiana University School of Medicine
  • Arvind Kunadi Assistant Program Director, McLaren Health Care
  • Uma Devi Avasarala Junior Research Officer, Asha Hospital
  • Shivangini Singh Junior Research Officer, Asha Hospital

Abstract

People suffering from cancer often suffer from anxiety, which is fuelled by worries about the future, side effects from therapy, and fear of recurrence. Through molecular mechanisms linked to stress, these psychological difficulties may affect cancer outcomes and lower quality of life. Although overlapping physical symptoms might make diagnosing anxiety difficult, validated instruments like the HADS and GAD-7 help in early detection. Younger age, unemployment, comorbidities, adverse effects from therapy, a lack of social support, financial distress and type of cancer are important risk factors. Effective strategies for reducing anxiety and enhancing emotional health include mindfulness-based exercises, cognitive behavioural therapy (CBT), acceptance and commitment therapy (ACT), and alternative therapies like yoga and tai chi. In severe situations, pharmacotherapy may be necessary. It’s critical to address obstacles like stigma, a lack of knowledge about mental health, and restricted access to care. Cancer survivors’ psychological resilience and general health outcomes can be improved by incorporating mental health management into survivorship care.

How to Cite

Gurugubelli, S., Rao, P., Mutyala, N., Kunadi, A., Avasarala, U. D., & Singh, S. (2025). Anxiety in Cancer Survivors. Indian Journal of Clinical Psychiatry, 5(02), 87–92. https://doi.org/10.54169/ijocp.v5i02.12

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References

1. Vargas-Román K, Díaz-Rodríguez CL, Cañadas-De la Fuente GA, Gómez-Urquiza JL, Ariza T, De la Fuente-Solana EI. Anxiety prevalence in lymphoma: A systematic review and meta-analysis. Health Psychol Off J Div Health Psychol Am Psychol Assoc. 2020 Jul;39(7):580–8.

2. Suzuki M, Deno M, Myers M, Asakage T, Takahashi K, Saito K, et al. Anxiety and depression in patients after surgery for head and neck cancer in Japan. Palliat Support Care. 2016 Jun;14(3):269–77.

3. Arch JJ, Genung SR, Ferris MC, Kirk A, Slivjak ET, Fishbein JN, et al. Presence and predictors of anxiety disorder onset following cancer diagnosis among anxious cancer survivors. Support Care Cancer. 2020 Sep 1;28(9):4425–33.

4. Wang X, Wang N, Zhong L, Wang S, Zheng Y, Yang B, et al. Prognostic value of depression and anxiety on breast cancer recurrence and mortality: a systematic review and meta-analysis of 282,203 patients. Mol Psychiatry. 2020 Dec;25(12):3186–97.

5. Spitzer RL, Kroenke K, Williams JBW, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006 May 22;166(10):1092–7.

6. Annunziata MA, Muzzatti B, Bidoli E, Flaiban C, Bomben F, Piccinin M, et al. Hospital Anxiety and Depression Scale (HADS) accuracy in cancer patients. Support Care Cancer Off J Multinatl Assoc Support Care Cancer. 2020 Aug;28(8):3921–6.

7. Suskin JA, Paul S, Stuckey AR, Conley YP, Miaskowski C, Dunn LB. Risk factors for worse anxiety trajectories among patients undergoing cancer chemotherapy. Support Care Cancer Off J Multinatl Assoc Support Care Cancer. 2022 Dec 15;31(1):32.

8. Braamse AMJ, van Turenhout ST, Terhaar Sive Droste JS, de Groot GH, van der Hulst RWM, Klemt-Kropp M, et al. Factors associated with anxiety and depressive symptoms in colorectal cancer survivors. Eur J Gastroenterol Hepatol. 2016 Jul;28(7):831–5.

9. Götze H, Friedrich M, Taubenheim S, Dietz A, Lordick F, Mehnert A. Depression and anxiety in long-term survivors 5 and 10 years after cancer diagnosis. Support Care Cancer Off J Multinatl Assoc Support Care Cancer. 2020 Jan;28(1):211–20.

10. Puigpinós-Riera R, Graells-Sans A, Serral G, Continente X, Bargalló X, Domènech M, et al. Anxiety and depression in women with breast cancer: Social and clinical determinants and influence of the social network and social support (DAMA cohort). Cancer Epidemiol. 2018 Aug;55:123–9.

11. Graells-Sans A, Serral G, Puigpinós-Riera R, Grupo Cohort DAMA. Social inequalities in quality of life in a cohort of women diagnosed with breast cancer in Barcelona (DAMA Cohort). Cancer Epidemiol. 2018 Jun;54:38–47.

12. Ye M, Du K, Zhou J, Zhou Q, Shou M, Hu B, et al. A meta-analysis of the efficacy of cognitive behavior therapy on quality of life and psychological health of breast cancer survivors and patients. Psychooncology. 2018 Jul;27(7):1695–703.

13. Mathew A, Doorenbos AZ, Jang MK, Hershberger PE. Acceptance and commitment therapy in adult cancer survivors: a systematic review and conceptual model. J Cancer Surviv Res Pract. 2021 Jun;15(3):427–51.

14. Xunlin NG, Lau Y, Klainin-Yobas P. The effectiveness of mindfulness-based interventions among cancer patients and survivors: a systematic review and meta-analysis. Support Care Cancer Off J Multinatl Assoc Support Care Cancer. 2020 Apr;28(4):1563–78.

15. Traeger L, Greer JA, Fernandez-Robles C, Temel JS, Pirl WF. Evidence-based treatment of anxiety in patients with cancer. J Clin Oncol Off J Am Soc Clin Oncol. 2012 Apr 10;30(11):1197–205.

16. Sakamoto R, Koyama A. Effective Therapy Against Severe Anxiety Caused by Cancer: A Case Report and Review of the Literature. Cureus. 12(6):e8414.

17. Popkin MK, Callies AL, Mackenzie TB. The outcome of antidepressant use in the medically ill. Arch Gen Psychiatry. 1985 Dec;42(12):1160–3.

18. Hardoerfer K, Jentschke E. Effect of Yoga Therapy on Symptoms of Anxiety in Cancer Patients. Oncol Res Treat. 2018;41(9):526–32.

19. Boppana SH, Kutikuppala LVS, Koirala SB, Konduru S, Thota V. Role of Mindfulness and Yoga in Cancer Management. In: Anand A, editor. Neuroscience of Yoga: Theory and Practice: Part II [Internet]. Singapore: Springer Nature; 2024 [cited 2025 Apr 14]. p. 167–80. Available from: https://doi.org/10.1007/978-981-97-2855-8_7

20. Kuang X, Dong Y, Song L, Dong L, Chao G, Zhang X, et al. The effects of different types of Tai Chi exercise on anxiety and depression in older adults: a systematic review and network meta-analysis. Front Public Health. 2023;11:1295342.

21. Kangas M, Heissel A. Mental health literacy, treatment preferences and the lived experience of mental health problems in an Australian cancer sample. Psychooncology. 2020 Nov;29(11):1883–94.

22. Dubreucq J, Plasse J, Franck N. Self-stigma in Serious Mental Illness: A Systematic Review of Frequency, Correlates, and Consequences. Schizophr Bull. 2021 Aug 21;47(5):1261–87.

23. Waumans RC, Muntingh ADT, Draisma S, Huijbregts KM, van Balkom AJLM, Batelaan NM. Barriers and facilitators for treatment-seeking in adults with a depressive or anxiety disorder in a Western-European health care setting: a qualitative study. BMC Psychiatry. 2022 Mar 5;22(1):165.